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Active Ingredient: Fluvoxamine

Luvox is indicated for the treatment of obsessions and compulsions in patients with obsessive compulsive disorder (OCD).

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Luvox is indicated for the treatment of obsessions and compulsions in patients with obsessive compulsive disorder (OCD). Luvox is a selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a natural substance in the brain, which helps to decrease anxiety and obsessive or compulsive behavior.


Use Luvox as directed by your doctor.

  • Take Luvox by mouth with or without food.
  • Take Luvox at bedtime unless your doctor tells you otherwise.
  • Continue to take Luvox if you feel well. Do not miss any dose.
  • Do not suddenly stop taking Luvox without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, dizziness, confusion, headache, trouble sleeping, or unusual tiredness. You will be closely monitored when you start Luvox and whenever a change in dose is made.
  • If you miss a dose of Luvox, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Luvox.


Store Luvox at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Avoid temperatures above 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Luvox out of the reach of children and away from pets.


Active Ingredient: Fluvoxamine maleate.

Safety information

Do NOT use Luvox if:

  • you are allergic to any ingredient in Luvox
  • you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or St. Johns wort within the last 14 days
  • you are taking alosetron, astemizole, a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, ramelteon, sibutramine, terfenadine, thioridazine, or tizanidine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Luvox. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
  • if you have a history of seizures, heart problems, liver problems, stomach or bowel bleeding, diabetes, blood or bone marrow problems, or metabolism problems
  • if you are dehydrated, have low blood sodium levels, or drink alcohol or smoke
  • if you will be having electroconvulsive therapy (ECT).

Some medicines may interact with Luvox. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anorexiants (eg, phentermine), fenfluramine derivatives (eg, dexfenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), medicines for mental problems (eg, quetiapine), metoclopramide, nefazodone, quinidine, rasagiline, selegiline, serotonin 5-HT1 receptor agonists (eg, sumatriptan), sibutramine, St. Johns wort, trazodone, or tryptophan because severe side effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur
  • Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding, including stomach bleeding, may be increased
  • Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood sodium levels may be increased
  • Tramadol because the risk of seizures may be increased
  • Astemizole, cisapride, phenothiazines (eg, chlorpromazine, thioridazine), pimozide, or terfenadine because severe heart problems, including irregular heartbeat, may occur
  • Cyproheptadine because it may decrease Luvoxs effectiveness
  • Alosetron, aripiprazole, benzodiazepines (eg, alprazolam, diazepam), beta-blockers (eg, metoprolol, propranolol), carbamazepine, clozapine, diltiazem, methadone, mexiletine, phenytoin, ramelteon, risperidone, serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, venlafaxine), tacrine, theophylline, tizanidine , or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Luvox.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Luvox may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Luvox may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Luvox with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Do not drink alcohol while you are using Luvox.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Luvox it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose, change your dose, or use Luvox for longer than prescribed without checking with your doctor.
  • Children, teenagers, and young adults who take Luvox may be at increased risk for suicidal thoughts or actions. Watch patients who take Luvox closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood anxious, restless, or irritable behavior panic attacks or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
  • If your doctor tells you to stop taking Luvox, you will need to wait for several weeks before beginning to take certain other medicines (eg, MAOIs, nefazodone). Ask your doctor when you should start to take your new medicines after you have stopped taking Luvox.
  • Serotonin syndrome is a possibly fatal syndrome that can be caused by Luvox. Your risk may be greater if you take Luvox with certain other medicines (eg, MAOIs, "triptans"). Symptoms may include agitation confusion hallucinations coma fever fast or irregular heartbeat tremor excessive sweating and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.
  • Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can rarely be caused by Luvox. Symptoms may include fever stiff muscles confusion abnormal thinking fast or irregular heartbeat and sweating. Contact your doctor at once if you have any of these symptoms.
  • Luvox may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
  • Caution is advised when using Luvox in the elderly they may be more sensitive to its effects, especially low blood sodium levels.
  • Luvox should be used with extreme caution in children safety and effectiveness in children have not been confirmed. They may be more sensitive to its effects, especially increased risk of suicidal thoughts or actions.
  • Luvox may cause weight changes. Children and teenagers may need regular weight and growth checks while they take Luvox.
  • Pregnancy and breast-feeding: Luvox may cause harm to the fetus if it is used during the last 3 months of pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Luvox while you are pregnant. Luvox is found in breast milk. Do not breastfeed while taking Luvox.

Side effects

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation decreased sexual ability diarrhea dizziness drowsiness dry mouth gas headache increased sweating loss of appetite nausea nervousness sore throat stomach upset trouble sleeping vomiting weakness.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash hives itching difficulty breathing tightness in the chest swelling of the mouth, face, lips, or tongue) bizarre behavior black or bloody stools chest pain confusion decreased concentration decreased coordination exaggerated reflexes fainting fast or irregular heartbeat fever hallucinations memory loss new or worsening agitation, anxiety, depression, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, or inability to sit still painful menstrual periods persistent, painful erection red, swollen, blistered, or peeling skin seizures severe or persistent headache or trouble sleeping stiff muscles stomach pain suicidal thoughts or attempts tremor unusual bruising or bleeding unusual or severe mental or mood changes unusual swelling unusual weakness vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.




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