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Purinethol

Active Ingredient: Mercaptopurine

Purinethol (Mercaptopurine) is used to treat leukemia.

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Description

INDICATIONS

Purinethol (Mercaptopurine) is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Mercaptopurine is used to treat certain types of leukemia. Mercaptopurine is sometimes given with other cancer medications.

Mercaptopurine may also be used for purposes not listed in this medication guide.

INSTRUCTIONS

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Mercaptopurine can lower blood cells that help your body fight infections. Your blood cells, kidney function, and liver function may need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow up visits to your doctor for blood or urine tests.

If you missed the dose take it as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

STORAGE

Store at room temperature away from moisture and heat.

MORE INFO:

Active Ingredient: Mercaptopurine

Safety information

Do not use mercaptopurine if you are pregnant. It could harm the unborn baby. You should not use mercaptopurine if you are allergic to it, or if you have ever used mercaptopurine or thioguanine (Tabloid) and they were not effective in treating your condition. Some people using mercaptopurine have developed a rare fast-growing type of lymphoma (cancer). This condition affects the liver, spleen, and bone marrow, and it can be fatal. This has occurred mainly in teenagers and young adults using mercaptopurine or similar medicines to treat Crohns disease or ulcerative colitis. Call your doctor at once if you have any of the following symptoms: fever, night sweats, itching, loss of appetite, weight loss, tiredness, feeling full after eating only a small amount, pain in your upper stomach that may spread to your shoulder, nausea, easy bruising or bleeding, pale skin, feeling light-headed or short of breath, rapid heart rate, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Mercaptopurine can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding injury. Tell your doctor at once if you develop signs of infection.

Important safety information

PURINETHOL (mercaptopurine) is a potent drug. It should not be used unless a diagnosis of acute lymphatic leukemia has been adequately established and the responsible physician is experienced with the risks of PURINETHOL and knowledgeable in assessing response to chemotherapy.

You should not use mercaptopurine if you are allergic to it, or if you have ever used mercaptopurine or thioguanine (Tabloid) and they were not effective in treating your condition. Some people using mercaptopurine have developed a rare fast-growing type of lymphoma (cancer). This condition affects the liver, spleen, and bone marrow, and it can be fatal. This has occurred mainly in teenagers and young adults using mercaptopurine or similar medicines to treat Crohns disease or ulcerative colitis.

Side effects

Get emergency medical help if you have any of these signs of an allergic reaction:

hives

difficulty breathing

swelling of your face, lips, tongue, or throat.

Stop using mercaptopurine and call your doctor right away if you have any of these symptoms of lymphoma:

fever, night sweats, weight loss, tiredness

feeling full after eating only a small amount

pain in your upper stomach that may spread to your shoulder

easy bruising or bleeding, pale skin, feeling light-headed or short of breath, rapid heart rate or

nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Stop using mercaptopurine and call your doctor at once if you have any of these other serious side effects:

signs of infection (fever, chills, sore throat, body aches, weakness, muscle pain, flu symptoms)

severe nausea, vomiting, or diarrhea

bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds

pain or burning with urination or

white patches or sores inside your mouth or on your lips.

Less serious side effects may include:

vomiting, mild diarrhea

hair loss

mild itching or skin rash or

darkened skin color.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.



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