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Relafen

Active Ingredient: Nabumetone

Relafen (Nabumetone), a nonsteroidal anti-inflammatory drug (NSAID), is used to treat the pain and swelling associated with arthritis.

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Description

INDICATIONS

Relafen belongs to a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing hormones that cause inflammation and pain in the body.

Relafen is used to treat pain or inflammation caused by arthritis.

Relafen may also be used for purposes other than those listed in this medication guide.

INSTRUCTIONS

Take Relafen exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

If you take Relafen for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.

DOSAGE

After observing the response to initial therapy with RELAFEN, the dose and frequency should be adjusted to suit an individual patient&rsquo s needs.

Osteoarthritis and Rheumatoid Arthritis

The recommended starting dose is 1,000 mg taken as a single dose with or without food. Some patients may obtain more symptomatic relief from 1,500 mg to 2,000 mg per day. RELAFEN can be given in either a single or twice-daily dose. Dosages greater than 2,000 mg per day have not been studied. The lowest effective dose should be used for chronic treatment (see WARNINGS, Renal Effects). Patients weighing under 50 kg may be less likely to require dosages beyond 1,000 mg therefore, after observing the response to initial therapy, the dose should be adjusted to meet individual patients&rsquo requirements.

Ask your physician how to use Relafen.

STORAGE

Store Relafen at room temperature away from moisture and heat.

MORE INFO:

Active Ingredient: Nabumetone

Relafen can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use Relafen. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.
Video: Rheumatoid Arthritis

This medicine can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking Relafen. Older adults may have an even greater risk of these serious gastrointestinal side effects.

Safety information

Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.
Do not use this medication if you are allergic to Relafen, or if you have a history of allergic reaction to aspirin or other NSAIDs.

Before taking Relafen, tell your doctor if you are allergic to any drugs, or if you have:

a history of heart attack, stroke, or blood clot

heart disease, congestive heart failure, high blood pressure

a history of stomach ulcers or bleeding

liver or kidney disease,

asthma

polyps in your nose

a bleeding or blood clotting disorder or

if you smoke.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take Relafen.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking Relafen during the last 3 months of pregnancy may harm the unborn baby. Do not take Relafen during pregnancy unless your doctor has told you to. It is not known whether Relafen passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child without the advice of a doctor.

Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to Relafen (such as ibuprofen, ketoprofen, or naproxen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, ketoprofen, or naproxen. Do not drink alcohol while taking Relafen. Alcohol can increase the risk of stomach bleeding caused by Relafen. Avoid prolonged exposure to sunlight. Relafen may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives difficulty breathing swelling of your face, lips, tongue, or throat. Stop taking Relafen and seek medical attention or call your doctor at once if you have any of these serious side effects:


chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance

black, bloody, or tarry stools

coughing up blood or vomit that looks like coffee grounds

swelling or rapid weight gain

urinating less than usual or not at all

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash or

bruising, severe tingling, numbness, pain, muscle weakness.

Less serious Relafen side effects may include:

upset stomach, mild heartburn or stomach pain, diarrhea, constipation

bloating, gas

dizziness, headache, nervousness

skin itching or rash

blurred vision or

ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.



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